Online GFR Calculators for Adults and Children

One of the best ways to detect early stages of chronic kidney disease (CKD) in adults is a blood test, which estimates GFR (Glomerular Filtration Rate) from serum creatinine. GFR is measure of how well your kidneys are filtering blood. Creatinine is a byproduct of creatine breakdown. Creatine is an integral part of muscle fibers.

Fully functioning kidneys normally eliminate creatinine out of the body through urine. However, once damage to the kidneys occurs, they will have a hard time releasing them. As a result, creatinine accumulates in the blood.

For adults, the best equation for estimating GFR from serum creatinine is the Modification of Diet in Renal Disease (MDRD) Study equation, according to the National Kidney Disease Education Program (NKDEP). This method of calculating GFR is used with routine creatinine methods.

For the online eGFR calculator, please visit the GFR MDRD Calculators for Adults (Conventional units)1,2 and the IDMS-traceable MDRD Study Equation GFR Calculator3 from the NKDEP site.

Please take note that the online eGFR calculator mentioned above is to be used only for adults, aged 18 and older.

The NKDEP website also offers an online eGFR calculator the can be used for children, called the Original Schwartz GFR Calculator for children4 and the Interim IDMS-traceable Schwartz GFR Calculator for children5.

Website: GFR Calculators. NKDEP, National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK). Available Online at http://www.nkdep.nih.gov/professionals/gfr_calculators/index.htm. Accessed on July 20, 2010

1 Levey AS, Greene T, Kusek J, and Beck G. A simplified equation to predict glomerular filtration rate from serum creatinine (abstract). J Am Soc Nephrol. 2000. 11: p.155A.

2Levey AS, Bosch JP, Lewis JB, Greene T, Rogers N, Roth D. A more accurate method to estimate glomerular filtration rate from serum creatinine: a new prediction equation. Modification of Diet in Renal Disease Study Group. Ann Intern Med. 1999 Mar 16;130(6):461–70.

3Levey AS, Coresh J, Greene T, Stevens LA, Zhang YL, Hendriksen S, Kusek JW, Van Lente F; Chronic Kidney Disease Epidemiology Collaboration. Using standardized serum creatinine values in the modification of diet in renal disease study equation for estimating glomerular filtration rate. Ann Intern Med. 2006 Aug 15;145(4):247–54.

4Schwartz GJ, et al. A simple estimate of glomerular filtration rate in children derived from body length and plasma creatinine. Pediatrics. 1976 Aug;58(2):259-63.

5Schwartz GJ, et al. Formulas to estimate GFR in children with chronic kidney disease. J Am Soc Nephrol. 2008, in press.

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